Thereareatleast20structurallyandfunctionallyrelatedBMPs,whicharemembersoftheTGF-betasuperfamily.BMPswereoriginallyidentifiedasproteinregulatorsofcartilageandboneformation.Theyarealsoinvolvedinembryogenesisandmorphogenesisofvarioustissuesandorgans.BMPsregulatethegrowth,differentiation,chemotaxisandapoptosisofvariouscelltypes,includingmesenchymalcells,epithelialcells,hematopoieticcellsandneuronalcells.SimilartootherTGF-betafamilyproteins,BMPsarehighlyconservedacrossanimalspecies.
Thisantibodyshowsapproximately25%cross-reactivitywithrhBMP-3andlessthan1%cross-reactivitywithrhBMP-2,rhBMP-4,rhBMP-5,rhBMP-6andrhBMP-7.
Image:BMP-6 stainingparaffin-embeddedhumanlungtissue.HRP-DABreagents(browncolor)wereusedforthedetection.Tissuesectionswerecounterstainedusinghematoxylin(blue).
OtherReagentstoConsider:AllStemCellReagents
Proteins:
BMP-2,Catalog#:PR15013
BMP-2,CarrierFree
BMP-2,E.ColiExpressed
BMP-2,E.ColiExpressed,CarrierFree
BMP-2,Catalog#:PR27023
BMP-4,Catalog#:PR27024
BMP-4,Catalog#:PR15015
BMP-4,CarrierFree
BMP-6
BMP-7
BMP-RType1A
AllProteins
Antibodies:
BMP-2/4
BMP-3b/GDF-10
BMP-3
BMP-4
BMP-5
BMP-5Monoclonal
BMP-7
BMP-8
GDF-3
GDF-5
BMPProteins
Noggin
AllStemCellReagents
Neurotrophins/GrowthFactors
Neuron/GlialMarkers
Diabetes/ObesityAntibodies
NeurodegenerativeDiseaseAntibodies
CancerAntibodies
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