Growthdifferentiationfactors(GDF-1toGDF-15)aremembersofthebonemorphogeneticprotein(BMP)family,withinthetransforminggrowthfactorbeta(TGF-beta)superfamily.GDF-5,-6,and-7share80-86%aasequenceidentitywitheachotheranddefineasubgroupwithintheBMPfamily.GDF-8ismostcloselyrelatedtoGDF-11with90%aasequenceidentity.Similarlytotheothermembersofthisfamily,theGDFsarehighlyconservedacrossspecies(withthepossIBLeexceptionofGDF-15).
Image:GDF-5stainingofcryostattissuesectionsE-12ofmouseembryos.Tissueswerestainedwithanti-goat HRP-DAB(brown)andHaematoxylin(blue)counterstain.
OtherReagentstoConsider:
BMP2/4
BMP-3
BMP-3b/GDF-10
BMP-4
BMP-5
BMP-5Monoclonal
BMP-6
BMP-7
BMP-8
GDF-3
BMPProteins
Noggin
AllStemCellReagents
Neurotrophins/GrowthFactors
Neuron/GlialMarkers
Diabetes/ObesityAntibodies
NeurodegenerativeDiseaseAntibodies
CancerAntibodies
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