Type:RabbitIgG
Applications:IF;IHC;FC
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:H;M;R
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:AffinityPurified-liquid
Immunogen:TASSSQPLLVHDDV
c-Kitistransmembranetyrosinekinaseencodedbythec-Kitprotooncogene.c-KitactstoregulateavarietyofBIOLOGical processesincludingcellproliferation,apoptosis,chemotaxisandadhesion.
Itplaysacriticalroleinactivationandgrowthinanumberofcelltypessuchashematopoieticstemcells,mastcells,melanocytesandgermcells.
Mutationsinc-Kithavebeenfoundtobeimportantfortumorgrowthandprogressioninavarietyofcancersincludingmastcelldiseases,gastrointestinalstromaltumor,acutemyeloidleukemia,Ewingsarcomaandlungcancer.Phosphorylationattyrosine721ofc-KitallowsbindingandactivationofPI3kinase.
Image:c-KITstainingofratskin(epidermis).c-KITdetectionwasdoneusinganti-rabbitCy3conjugatedantibodies(redcolor).DAPIwasusedtocounterstaincellnuclei(bluecolor).Workingdilution:1:100-1:300.
c-Kit:CustomerPublications
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Neuromics因为是由一批顶尖的学术和商业实验室挑选，试验和创新他们的 试剂来满足顾客的需要而使自己的表现尤为突出。Neuromics从 以上过程中获得的经验使得顾客****的实际应用和试剂独特的性能能够得以相容。它精通于提供试剂和为神经科学研究机构提供产品和服务。
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