Type:GuineaPigIgG
Applications:ICC;IHC
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:R
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:Wholeserum-liquid
Immunogen:TVGTHNGLEHSTFNMTIEPGRVQAYC
Neurotensinreceptor1(NTSR1)belongstothelargesuperfamilyofG-proteincoupledreceptors.NTSR1mediatesthemultiplefunctionsofneurotensin,suchashypotension,hyperglycemia,hypothermia,antinociception,andregulationofintestinalmotilityandsecretion.NTR1hasbeenreportedinbrain,pancreas,andsmallintestine.ESTshavebeenisolatedfrombrainandcolonlibraries
CustomerData andPublicationsonNeurotensinReceptor1
Images:ExpressionofNTS1receptorsinsensoryneuronsandspinalcord.(a)ImmunoperoxidasestainingrevealsthepresenceofNTS1-likeimmunoreactivitythroughoutthelumbardorsalhornofthespinalcord.Immunolabelingismostprominentinthesuperficiallayersofthedorsalhorn.Thelateralspinalnucleus(lsn)isalsomoderatelylabeled(arrow).(b)Highmagnificationof(a).AdenseNTS1immunostainingisobservedoverlaminaeIandIIofthedorsalhorn.NumerousimmunopositivenervecellbodiesarevisIBLeinthesuperficiallaminaeandinthenucleuspropriusofthedorsalhorn(arrows).(c)LightmicroscopicanalysisofNTS1expressioninprimaryafferentneurons.NTS1isexpressedinsubpopulationsofsmall-andmedium-ganglioncells.NoapparentlabelingisdetectedinlargeDRGneurons(arrows).Athighermagnification,NTS1neuronsexhibitacytoplasmicpatternofimmunoreactivity(d,arrowheads).(e)IdentificationofendogenouslyexpressedNTS1receptors,bywesternblotting,inhomogenatesfromDRGs,lumbarspinalcordandbrain.The47kDaproteinbandcorrespondstothemolecularweightdeducedfromtheCDNAsequenceofNTS1.Eachlanerepresentsthetransferof25lgofprotein.Scalebars:(a,b,c,andd)300,150,70and20lm,respectively.doi:10.1111/j.1471-4159.2007.05205.x.
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