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主营:神经科学、干细胞以及再生医学研究试剂
℡ 4000-520-616
℡ 4000-520-616
Neuromics/IL-1 beta (Rat)/GT15105/100 ug
产品编号:GT15105-100ug
市  场 价:¥7300.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$365.00
品      牌: Neuromics
公      司:Neuromics
公司分类:
Neuromics/IL-1 beta (Rat)/GT15105/100 ug
商品介绍

Type:GoatIgG

 

Applications:E;ICC;WB;NB

E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssays

SpeciesReactivity:R

B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All

Format:AffinityPurified-liquid

 

Immunogen:purified,E.coli-derived,recombinantratinterleukin1beta.

 

Picture

TheInterleukin1receptorfamily(IL-1R)comprisesatleastninemembersincludingIL-1R1,IL-1R2(IL-1RII),IL-1R3(IL-1RAcP),IL-1R4(ST2/T1),IL-1R5(IL-18Ralpha/IL-1Rrp),IL-1R6(IL-1Rrp2/IL-1RL2),IL-1R7(AcPL/IL-18Rb),IL-1R8(TIGIRR-2)andIL-1R9(TIGIRR-1).Allfamilymemberspossessthreeimmunoglobulin(Ig)-likedomainsintheirextracellularregion.MostmembersalsohaveanintracellularTIR(Toll-likereceptor/IL-1receptor)signalingdomainthatisalsoconservedintheToll-likereceptorfamily.AsubtypeoftheIL-1Rfamily,SIGIRR(singleIgdomain-containingIL-1R-relatedmolecule)whichdiffersfromtheotherninemembersbyhavingonlyoneIgdomain,hasalsobeenidentified.SeeIL-18RalphaforIL-1R5andIL-18RbetaforIL-1R7.

Image:IL-1betawasdetectedinLPS-stimulatedratsplenocytes.Cellswerestainedusinganti-goatIgGsecondaryantibody(red)andcounterstainedwithFluoroNissl™*Green.

*FluoroNisslisatrademarkofMolecularprobes.
Picture[2]

Figure1:RatIL-1βstimulates3H-thymidineincorporationbymurineT-helperD10.G4.1cellsinadose-dependentmanner(Symons,J.A.etal.,1987,inLymphokinesandInterferons,APracticalApproach,IRLPress,M.J.Clemens,A.G.MorrisandA.J.H.Gearing,eds.p.272).TheED50forthiseffectistypically1-3ng/mL.

Figure2:Approximately0.5-2.0μg/mLoftheantibodywillneutralize50%ofthebioactivitydueto10ng/mLofratIL-1β.TheND50forthislotofanti-ratIL-1βantibodywasdeterminedtobeapproximately0.5-2μg/mLinthepresenceof10ng/mLofrrIL-1β,usingthemurineT-helpercellline,D10.G4.1.Thespecificconditionsaredescribedinthefigurelegends.

品牌介绍

Neuromics公司提供一系列高品质新蛋白的抗体、神经干细胞及培养基、神经干细胞扩增及分化试剂盒、干细胞抗体、神经和前体细胞流式分型试剂、细胞凋亡研究试剂、荧光激活细胞分拣法试剂盒、细胞内部试剂盒、转染试剂、ELISA 缓冲稀释液与IHC-WB-ELISA 补充物等试剂。

Neuromics因为是由一批顶尖的学术和商业实验室挑选,试验和创新他们的 试剂来满足顾客的需要而使自己的表现尤为突出。Neuromics从 以上过程中获得的经验使得顾客****的实际应用和试剂独特的性能能够得以相容。它精通于提供试剂和为神经科学研究机构提供产品和服务。


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