Neuromics/ASIC 3/GP14105/50 ul,Neuromics,,Neuromics,Neuromics INC,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Neuromics/ASIC 3/GP14105/50 ul

产品编号：GP14105-50ul

市场价：¥3800.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$190.00

品牌： Neuromics

公司：Neuromics

公司分类：

商品介绍

Type:GuineaPigIgG

Applications:ICC;IHC

E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssays

SpeciesReactivity:R

B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All

Format:Wholeserum-liquid

Immunogen:(C)TASLDPDDFDPEPSDPLGSP

Theacid-sensingionchannelfamily(ASIC)comprisessixdiscreteASICsubunits(ASIC1A,ASIC1B,ASIC2A,ASIC2B,ASIC3,ASIC4)thatdetecttissueacidosis(i.e.adecreaseinpH).Thisacidosisphenomenon isa responsetotissueinjury,pain andinflammation.

Figure:ASIC3expressioncomparedtoothernociceptiveionchannels.DRGsectionsdouble-labeledforASIC3(red)andeitherP2X3(green,A)orTRPV1(green,B);double-labeledcellsareyellowororange.CirclechartsshowtherelativedistributionofthethreereceptorsamongallDRGneurons.ASIC3andP2X3expressionoverlappedinonly4%ofneurons,whilesome35%ofASIC3-positiveneuronsalsoexpressTRPV1.TherarecellspositiveforbothASIC3andP2X3werelarge(eg.cellatlowerleftinA).1406cellscountedforA;995forB.C,D,electrophysiologicalrecordingsrevealaqualitativelysimilarexpressionpatternforcurrentsconformingtoASIC3,P2X3,orTRPV1.ThecellthatgeneratedthecurrentsinCcountsasaco-expressorofASIC3andP2X3,fittingintotheyellowbininthecircleplot.ThecellinDisaco-expressorofASIC3andTRPV1.Cellswerecountedpositiveiftheyhadatleast0.3nAofcurrentinresponsetopH6.8(ASIC3+),50μMATP(P2X3+;transientcurrentonly),or1μMcapsaicin(TRPV1).182cellsrecordedforC;169forD.

ASIC3:CustomerPublications

品牌介绍

Neuromics公司提供一系列高品质新蛋白的抗体、神经干细胞及培养基、神经干细胞扩增及分化试剂盒、干细胞抗体、神经和前体细胞流式分型试剂、细胞凋亡研究试剂、荧光激活细胞分拣法试剂盒、细胞内部试剂盒、转染试剂、ELISA 缓冲稀释液与IHC-WB-ELISA 补充物等试剂。

Neuromics因为是由一批顶尖的学术和商业实验室挑选，试验和创新他们的试剂来满足顾客的需要而使自己的表现尤为突出。Neuromics从以上过程中获得的经验使得顾客****的实际应用和试剂独特的性能能够得以相容。它精通于提供试剂和为神经科学研究机构提供产品和服务。

公司介绍

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