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主营:神经科学、干细胞以及再生医学研究试剂
℡ 4000-520-616
℡ 4000-520-616
Neuromics/Kv7.2/KCNQ2 K+ channel/MO50023/100 ul
产品编号:MO50023-100ul
市  场 价:¥8100.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$405.00
品      牌: Neuromics
公      司:Neuromics
公司分类:
Neuromics/Kv7.2/KCNQ2 K+ channel/MO50023/100 ul
商品介绍

Type:MouseIgG

 

Applications:IF;IHC;WB

E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssays

SpeciesReactivity:H;M;R

B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All

Format:AffinityPurified-liquid

 

Immunogen:Fusionproteinaminoacids1-59(cytoplasmicN-terminus)ofhumanKv7.2orKCNQ2K+channel(accessionnumberO43526).

 

Picture

Voltage-gatedK+channelsareimportantdeterminantsofneuronalmembraneexcitABIlity.Moreover,differencesinK+channelexpressionpatternsanddensitiescontributetothevariationsinactionpotentialwaveformsandrepetitivefiringpatternsevidentindifferentneuronalcelltypes(Maletic-Savaticetal.,1995;Pongs,1999;BlaineandRibera,1998;BurgerandRibera,1996).Kv7.2/KCNQK+channelsassociatewithKv7.3/KCNQ3K+channlestoformapotassiumchannelwithessentiallyidenticalpropertiestothechannelunderlyingthenativeM-current,aslowlyactivatinganddeactivatingpotassiumconductancewhichplaysacriticalroleindeterminingthesubthresholdelectricalexcitabilityofneuronsaswellastheresponsivenesstosynapticinputs. 

Images:Kv7.2(dilution1:100)stainingofratskinslicedinto40μmcryo-sections(red)andcounterstainedwithNF-H(green)doi:10.3389/fnmol.2012.00063.

Defectsin Kv7.2arethecauseofbenignfamilialneonatalseizurestype1(BFNS1). Itisalsoexpressedintheperipheralterminalsofnociceptiveprimaryafferents.

品牌介绍

Neuromics公司提供一系列高品质新蛋白的抗体、神经干细胞及培养基、神经干细胞扩增及分化试剂盒、干细胞抗体、神经和前体细胞流式分型试剂、细胞凋亡研究试剂、荧光激活细胞分拣法试剂盒、细胞内部试剂盒、转染试剂、ELISA 缓冲稀释液与IHC-WB-ELISA 补充物等试剂。

Neuromics因为是由一批顶尖的学术和商业实验室挑选,试验和创新他们的 试剂来满足顾客的需要而使自己的表现尤为突出。Neuromics从 以上过程中获得的经验使得顾客****的实际应用和试剂独特的性能能够得以相容。它精通于提供试剂和为神经科学研究机构提供产品和服务。


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