Type:Protein
SpeciesReactivity:H
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All
MIFhumanRecombinant,fusedtoHis-tagatN-terminus,wasclonedintoanE.coliexpressionvectorandwaspurifiedtoapparenthomogeneitybyusingconventionalcolumnchromatographytechniques.MacrophageInducingFactorHumanRecombinantisasingle,glycosylated,polypeptidechainhavingaminoacidsfrom1-114andhavingamolecularmassof16.6kDa.
Image:MIFStructureandSequence..
References:
1.Directeffectofmacrophagemigrationinhibitoryfactoronspermfunction:possIBLeinvolvementinendometriosis-associatedinfertility. FertilSteril2007Jul19.
2.IncreasedserumlevelsofmacrophagemigrationinhibitoryfactorinpatientswithKawasakidisease. ScandJRheumatol2007May-Jun;36(3):222-5.
3.Roleofmacrophagemigrationinhibitoryfactorincornealneovascularization. InvestOphthalmolVisSci2007Aug;48(8):3545-50.
4.NullmutationforMacrophageMigrationInhibitoryFactor(MIF)isassociatedwithlessaggressivebladdercancerinmice. BMCCancer2007Jul24;7(1):135.
5.Theroleofmacrophagemigrationinhibitoryfactorinmaintainingtheimmuneprivilegeatthefetal-maternalinterface. SeminImmunopathol2007Jun;29(2):135-50
6.[Serumlevelsofmacrophagemigrationinhibitoryfactorandinterleukin-8inhepatocellularcarcinomapatients:theircorrelationswithtumorprogressionandprognosis.] ZhonghuaGanZangBingZaZhi2007Jun;15(6):463-4.
Image: MIF-Human structureandsequence
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