Vascularendothelialgrowthfactor(VEGF),alsoknownasvascularpermeABIlityfactor(VPF)orvasculotropin,isahomodimeric34-42kDa,heparin-bindingglycoproteinwithpotentangiogenic,mitogenicandvascularpermeability-enhancingactivitiesspecificforendothelialcells.TheaminoacidsequenceofVEGFexhibitsprimarystructural,aswellaslimitedaminoacidsequence,homologywiththatoftheAandBchainsofPDGF.Alleightcysteineresiduesinvolvedinintra-andinter-chaindisulfidebondsareconservedamongthesegrowthfactors.ACDNAencodingaproteinhavinga53%aminoacidsequencehomologyinthePDGF-likeregionofVEGFhasbeenisolatedfromahumanplacentalcDNAlibrary.Thisprotein,namedplacentagrowthfactor(PlGF),isnowrecognizedtobeamemberoftheVEGFfamilyofgrowthfactors.BasedonitshomologywithVEGF,PlGFwasalsoproposedtobeanangiogenicfactor.TworeceptortyrosinekinaseshavebeendescribedasputativeVEGFreceptors.Flt-1(fms-liketyrosinekinase),andKDR(kinase-insert-domain-containingreceptor)proteinshavebeenshowntobindVEGFwithhighaffinity.
Neuromics公司提供一系列高品质新蛋白的抗体、神经干细胞及培养基、神经干细胞扩增及分化试剂盒、干细胞抗体、神经和前体细胞流式分型试剂、细胞凋亡研究试剂、荧光激活细胞分拣法试剂盒、细胞内部试剂盒、转染试剂、ELISA 缓冲稀释液与IHC-WB-ELISA 补充物等试剂。
Neuromics因为是由一批顶尖的学术和商业实验室挑选,试验和创新他们的 试剂来满足顾客的需要而使自己的表现尤为突出。Neuromics从 以上过程中获得的经验使得顾客****的实际应用和试剂独特的性能能够得以相容。它精通于提供试剂和为神经科学研究机构提供产品和服务。