Type:Protein
SpeciesReactivity:M
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All
GM-CSFstimulatesthegrowthanddifferentiationofhematopoieticprecursorcellsfromvariouslineages,includinggranulocytes,macrophages,eosinophilsanderythrocytes.
Image: GM-CSF MouseStructureandSequence.
References:
1.Granulocyte-macrophagecolonystimulatingfactorandinterleukin-8inthereproductivetractofewesfollowingoestrusandmating ReprodFertilDev2007;19(4):585-93.
2.Useofgranulocyte-macrophagecolony-stimulatingfactortoreverseanergyinotherwiseimmunologicallyhealthychildren.AnnAllergyAsthmaImmunol2007Apr;98(4):373-82.
3.[Plasmagranulocyte-macrophagecolonystimulatingfactor(GM-CSF)andactivityofenzymesingranulocytesofbreastcancerpatients]PrzeglLek2006;63(8):654-7.
4.Granulocyte-macrophagecolony-stimulatingfactor(CSF)andmacrophageCSF-dependentmacrophagephenotypesdisplaydifferencesincytokineprofilesandtranscriptionfactoractivities:implicationsforCSFblockadeininflammation.JImmunol2007Apr15;178(8):5245-52.
5.Granulocytecolony-stimulatingfactorandgranulocytemacrophagecolony-stimulatingfactorexacerbateatherosclerosisinapolipoproteinE-deficientmice. Circulation2007Apr17;115(15):2049-54.
6.Re:ClinicalandimmunologicalcharacteristicsofpatientswithSEROlogicprogressionofprostatecancerachievinglong-termdiseasecontrolwithgranulocyte-macrophagecolony-stimulatingfactor:B.I.Rini,L.Fong,v.Weinberg,B.KavanaughandE.J.Small.JUrol2006;175:2087-2091. JUrol2007Apr;177(4):1585;authorreply1585-6.
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